The International Max Planck Research School for Living Matter (IMPRS-LM, formerly IMPRS-CMB) is a collaboration between the Max Planck Institute of Molecular Physiology and three universities, the Technical University Dortmund (TU Dortmund), the Ruhr University Bochum (RUB) and the University of Duisburg-Essen (DUE).

All four institutes are located in the Ruhr Metropolitan Area of Germany, an extremely vibrant and culturally interconnected region. The same spirit is reflected in the science of our program: research groups, with different and often complementary approaches, combine their efforts to study at the molecular level basic cell physiology.

Below you can find all the research groups that are part of IMPRS-LM, in alphabetical order. You can also search groups by name, topic or technique.

Read about OUR SCIENCE by visiting the webpages of our Faculty Members.

Faculty Members

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Prof. Dr. Philippe I.H. Bastiaens

IMPACT OF DYNAMICS AND SPATIAL ORGANIZATION OF SIGNALLING MOLECULES/ACTIVITIES ON CELL PHENOTYPE

Systems Biology
Biophysical Chemistry

Cell Biology, Molecular Biology, Network Biology, Synthetic Biology, Theory of Complex Systems

Dr. Sidney Becker

The principles of molecular evolution - from fundamental mechanisms to molecular diagnostics

Innovation in DNA sequencing
In vitro evolution (SELEX)

nucleic acid chemistry, molecular medicine, chemical biology, biochemistry

Dr. Peter Bieling

CELL POLARITY AND MORPHOGENESIS


Prof. Dr. Dominik Boos

VERTEBRATE DNA REPLICATION


Dr. habil. Leif Dehmelt

SPATIO-TEMPORAL REGULATION OF THE NEURONAL CYTOSKELETON


Prof. Dr. Michael Ehrmann

PROTEIN QUALITY CONTROL


Prof. Dr. Ralf Erdmann

PROTEIN IMPORT INTO PEROXISOMES


Dr. Malte Gersch

CHEMICAL BIOLOGY

Ubiquitin system
Proteostasis

SMALL MOLECULE MODULATORS , POST-TRANSLATIONAL MODIFICATIONS, CHEMICAL SYNTHESIS, CELL SIGNALING, BIOCHEMISTRY

Prof. Dr. Klaus Gerwert

CHAIR OF BIOPHYSICS AT RUHR UNIVERSITY BOCHUM


Dr. Doris Hellerschmied

PROTEIN HOMEOSTASIS IN THE GOLGI

Biochemistry
Cellular Stress

Chemical and Genetical perturbation; protein structure and function; proteostasis; cell biology; protein engineering expression and purification

Matías Hernández, PhD

CELL-CELL MEMBRANE FUSION

Molecular Biology
Cell Fusion

molecular machines, yeast genetics, biochemical assays, fluorescence microscopy

Dr. Jochen Imig

SYSTEMS BIOLOGY OF NON-CODING RNA NETWORKS IN CANCER

ncRNAs
Cancer

CRISPR; genome editing; miRNA; lncRNA

Prof. Dr. Markus Kaiser

ELUCIDATION OF THE MODE-OF-ACTION OF NATURAL PRODUCTS


Prof. Dr. Müge Kasanmascheff

Biophysical Chemistry and Biocatalysis

EPR spectroscopy
Protein Structure and Function

metalloproteins; in-cell spectroscopy; physical chemistry; protein engineering, expression and purification

Prof. Dr. Stefan M. Kast

THEORETICAL PHYSICAL CHEMISTRY

Small Molecule Modulators
Protein Structure and Funtion

MODELING AND SIMULATIONS, COMPUTATIONAL CHEMISTRY, PHYSICAL CHEMISTRY, DRUG DEVELOPMENT

Dr. Katarzyna Kliza

Post-translational modification networks

ADP-Ribosylation
Proteomics

Biochemistry; Molecular Biology; Systems Biology; Post-translational modifications

Prof. Dr. Rasmus Linser

NMR-based Structural Biology

Protein Structure Dynamics and Function
Innovation of NMR Technology

enzyme, function, interaction, biochemistry, spectroscopy

Prof. Dr. Hemmo Meyer

CELLULAR HOMEOSTASIS, PROLIFERATION AND STRESS RESPONSES


Prof. Dr. Andrea Musacchio

CELL DIVISION IN VITRO AND IN VIVO


Prof. Dr. Hannes Mutschler

Biomimetic Chemistry

Synthetic Biology
Nucleic Acid Catalysis

Biochemistry; Molecular Biology; Biophysics; Microbiology

Prof. Dr. Boris Pfander

Cell Biology

Genome Integrity
Genetic Engineering

CELL BIOLOGY; DNA REPLICATION; DNA DAMAGE and REPAIR; NEXT GENERATION SEQUENCING

Prof. Dr. Daniel Rauh

Chemical and Molecular Oncology

Chemical Biology
Medicinal Chemistry

Structural biology, Cancer drug discovery, Protein Structure and function, Screening

Prof. Dr. Stefan Raunser

STRUCTURAL BIOCHEMISTRY

Structural Biology

Cytoskeleton, Host-Pathogen Interaction, Protein Structure and Function, Cryo-Electron Microscopy, Image Processing, X-ray crystallography

Prof. Dr. Barbara Saccà

BIONANOTECHNOLOGY

DNA Nanotechnology
Nanomaterials and Supramolecular Chemistry

MOLECULAR SELF-ORGANIZATION; PATTERN FORMATION; SPATIAL ORGANIZATION; BIOPHYSICS; BIOCONJUGATES

Dr. Christian Schröter

CELL COMMUNICATION AND FATE DECISIONS

Stem Cell Biology
Cell Signalling

cell fate decisions, intercellular communication, pattern formation, live cell imaging, Systems biology

Prof Dr. Frank Schulz

CHEMISTRY AND BIOCHEMISTRY OF NATURAL PRODUCTS


Prof. Dr. Daniel Summerer

NUCLEIC ACID CHEMICAL BIOLOGY

Chemical Biology
Epigenetics

Directed Molecular Evolution, Synthetic Biology, Unnatural Amino Acids, Nucleic Acid Chemistry, Optogenetics

Dr. Peter 't Hart

BIOMACROMOLECULAR INTERACTIONS

Chemical Biology
Macromolecular Interactions

Peptide synthesis, Cell-based assays, Epigenetics, Screening, Biophysics

Prof. Dr. Jörg Tatzelt

BIOCHEMISTRY OF NEURODEGENERATIVE DISEASES

Biochemistry
Neurodegenerative Diseases

ORGANELLES AND INTERORGANELLE COMMUNICATION, PROTEOSTASIS, CELLULAR STRESS, PROTEIN STRUCTURE AND FUNCTION, FLUORESCENCE MICROSCOPY

Prof. Dr. Britta Trappmann

Complex 3D Cellular Systems

Tissue engineering
Cell-matrix interactions

biomaterials; 3D cell culture; fluorescence microscopy; cell-based assays

Dr. Ingrid Vetter

CRYSTALLOGRAPHY


Prof. Dr. Herbert Waldmann

DEPARTMENT OF CHEMICAL BIOLOGY

Chemical Biology
Synthetic Chemistry

biochemistry, cell biology, computational chemistry, medicinal chemistry

Prof. Dr. Stefan Westermann

KINETOCHORES AND THE MICROTUBULE CYTOSKELETON


Prof. Dr. Konstanze F. Winklhofer

MOLECULAR CELL BIOLOGY


Dr. Peng Wu

CHEMISTRY AND CHEMICAL BIOLOGY

Small Molecule Probes and Drugs
Structurally Diverse Synthesis

Protein RNA Interactions, Kinase Inhibitors, Cell Signaling Modulators, Organic Synthetic Methodology, Medicinal Chemistry

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